The Prokaryotic Genome Annotation Pipeline
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Contact: [email protected] NCBI Handout Series | Prokaryotic Genome Annotation Pipeline | Last Updated on May 25, 2017 Introduction Genome annotation is a complex process that includes prediction of protein-coding genes and other functional genome units, i.e., structural RNAs, tRNAs, small RNAs, pseudogenes, control regions, direct and inverted repeats, insertion sequences, as well as transposons and other mobile elements. The NCBI Prokaryotic Genome Annotation Pipeline is designed to annotate bacterial and archaeal complete and draft genomes using a combination of ab initio gene prediction and homology based methods (NBK147280). This annotation pipeline, capable of processing a large data volume and currently being used by NCBI’s RefSeq project, is offered as an annotation service to GenBank submitters. This service is unavailable for download or usage outside the NCBI submission portal due to its system and database dependencies.
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